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KMID : 1001920130530030197
Journal of Korean Neurosurgical Society
2013 Volume.53 No. 3 p.197 ~ p.200
Cerebral Syphilitic Gumma Mimicking a Brain Tumor in the Relapse of Secondary Syphilis in a Human Immunodeficiency Virus-Negative Patient
Yoon Young-Kyung

Kim Min-Ja
Chae Yang-Seok
Kang Shin-Hyuk
Abstract
Diagnosis of cerebral syphilitic gumma is frequently determined at the time of surgery, because imaging and laboratory findings demonstrate the elusive results. A 59-year-old woman presenting dysarthria showed a mass on her brain computed tomography. She was first suspected of brain tumor, but histological results from surgical resection revealed cerebral gumma due to neurosyphilis. After operation, she presented fever and rash with an infiltration on a chest X-ray. Histological assessment of skin was consistent with syphilis. Fluorescent treponemal antibody absorbed test IgG in cerebrospinal fluid was positive. She was successfully treated with ceftriaxone for 14 days.
KEYWORD
Gummatous neurosyphilis, Latent syphilis, HIV negative, Ceftriaxone
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